This study compared these treatments for primary hyperparathyroidism: parathyroidectomy (47 dogs), percutaneous ultrasonography-guided ethanol ablation (15 dogs), and percutaneous ultrasonography-guided heat ablation (48 dogs). Treatment was judged successful if complete resolution of hypercalcemia was documented at 6 and 90 days after therapy. The responses for all 3 methods were good. There was no statistically significant difference between the success rates for parathyroidectomy and heat ablation, but parathyroidectomy and ethanol ablation did significantly differ. The only complication for the parathyroidectomy group was hypocalcemia, while some dogs in the other treatment groups experienced cough, change in bark, or Horner's syndrome.

COMMENTARY: Although surgery still appears to be the best treatment method for primary hyperparathyroidism, other methods may be good alternatives, especially with an experienced person.

Retrospective evaluation of three treatment methods for primary hyperparathyroidism in dogs. Rasor L, Pollard R, Feldman E. JAAHA 43:70-77, 2007.