Cytauxzoon felis is a protozoal parasite that infects the blood of domestic and wild cats in various regions of the United States. Infected ticks can transmit the parasite to cats while feeding; the parasite then replicates in the cat and spreads throughout the body. Infected cats may be subclinically affected, but clinical signs can include anorexia, depression, lethargy, dehydration, pyrexia, dyspnea, icterus, dark urine, pallor, anemic heart murmur, and increased capillary refill time. Hematology may reveal a normocytic, normochromic, nonregenerative anemia with pancytopenia or moderate neutrophilia.
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