For a 2-month period, a 1.5-year-old spayed female golden retriever had been evaluated for pollakiuria and hematuria. The dog showed no response to 4 different antibiotics. On initial physical examination, the dog looked healthy and had good body condition. Abdominal ultrasonography revealed a large, irregularly shaped intraluminal mass in the urinary bladder. During surgery, all the abdominal organs looked normal except for the bladder. Multiple pedunculated, firm, pink masses were arising from the bladder mucosa. The masses were removed, and tube cystostomy was performed.Grade 3 leiomyosarcoma was diagnosed histopathologically, with the lesionextending to the surgical margins. An ultrasound examination 2 weeks after surgery revealed that the tumorwas recurring. The owners declined chemotherapy but continued to use the cystotomy tube to keep the dog comfortable.
COMMENTARY: Tumors of the urinary bladder are more common in older dogs. The most common tumor in the lower urinary tract is the transitional cell carcinoma. Leiomyosarcomas are rarely reported in dogs and are highly malignant and infiltrative into surrounding tissues. The history of chronic hematuria and pollakiuria in this patientemphasizes the importance of further diagnostic procedures to determine the cause when there is no response to initial therapy.
Persistent urinary problems in a young golden retriever. Goett SD, Degner DA. VET MED 98:839-842, 2003.