Content continues after advertisement

Pugs, Papillomaviruses, & Plaques

Alison Diesel, DVM


|September 2008

Sign in to Print/View PDF

Four unrelated European pugs were examined because of lesions on the ventral abdomen and legs. Lesions were slightly raised, deeply pigmented, and hyperkeratotic. Histologic examination did not reveal any evidence of viral inclusions; however, polymerase chain reaction (PCR) testing identified a novel canine papillomavirus (CPV4). This virus is distinct from oral PV and from other previously isolated CPVs. Study funded in part by the Waltham Foundation.

COMMENTARY: The article raises several key issues of which veterinarians and pug owners should be aware. The novel CPV documented in the 4 pugs in this study is distinct from the more common CPVs in the sense that it does not seem to be infectious. Further study needs to be done on its exact mode of inheritance. A hyperpigmented mass or lesion in a pug should prompt the clinician to pursue biopsy and potentially PCR testing. Most other breeds have a high degree of neoplastic findings with hyperpigmented masses (strong suspicion of melanoma), whereas the lesions here were not malignant. This may be very good news for pugs and their owners!

Detection of a novel papillomavirus in pigmented plaques of four pugs. Tobler K, Lange C, Carlotti N, et al. VET DERMATOL 19:21-25, 2007.

For global readers, a calculator to convert laboratory values, dosages, and other measurements to SI units can be found here.

All Clinician's Brief content is reviewed for accuracy at the time of publication. Previously published content may not reflect recent developments in research and practice.

Material from Clinician's Brief may not be reproduced, distributed, or used in whole or in part without prior permission of Educational Concepts, LLC. For questions or inquiries please contact us.


Clinician's Brief:
The Podcast
Listen as host Alyssa Watson, DVM, talks with the authors of your favorite Clinician’s Brief articles. Dig deeper and explore the conversations behind the content here.
Clinician's Brief provides relevant diagnostic and treatment information for small animal practitioners. It has been ranked the #1 most essential publication by small animal veterinarians for 9 years.*

*2007-2017 PERQ and Essential Media Studies

© 2023 Educational Concepts, L.L.C. dba Brief Media ™ All Rights Reserved. Terms & Conditions | DMCA Copyright | Privacy Policy | Acceptable Use Policy