Fluralaner, a novel, systemic ectoparasiticide, provides dogs with immediate control of fleas and ticks and persists in the system for 12 weeks. Because of their potential concurrent use, this study analyzed pharmacokinetic profiles of fluralaner and ivermectin given alone and in conjunction. Neither drug’s pharmacokinetic profile was altered, and concurrent use did not increase the risk for ivermectin-associated neurotoxicity.
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