Content continues after advertisement

Therapeutics Research Note: Mycophenolate Mofetil & Prednisone


|February 2017

Sign in to Print/View PDF

Meningoencephalomyelitis of unknown etiology (MUE) is treated with prednisone, either alone or in combination with other immunosuppressive drugs. Mycophenolate mofetil (MMF) has been used to treat MUE in dogs but has not been assessed in a larger-scale study. 

This retrospective case series described the response, adverse events, and outcomes associated with combination MMF–prednisone treatment for MUE. Partial or complete response was achieved in 95% of dogs. Hemorrhagic diarrhea was the most commonly described side effect (20%). Treatment was stopped within 14 days in affected dogs, and those cases were excluded from further statistical analysis. Larger-scale controlled prospective studies are warranted to evaluate the efficacy of MMF as an adjunct treatment for MUE.


For global readers, a calculator to convert laboratory values, dosages, and other measurements to SI units can be found here.

All Clinician's Brief content is reviewed for accuracy at the time of publication. Previously published content may not reflect recent developments in research and practice.

Material from Clinician's Brief may not be reproduced, distributed, or used in whole or in part without prior permission of Educational Concepts, LLC. For questions or inquiries please contact us.


Clinician's Brief:
The Podcast
Listen as host Alyssa Watson, DVM, talks with the authors of your favorite Clinician’s Brief articles. Dig deeper and explore the conversations behind the content here.
Clinician's Brief provides relevant diagnostic and treatment information for small animal practitioners. It has been ranked the #1 most essential publication by small animal veterinarians for 9 years.*

*2007-2017 PERQ and Essential Media Studies

© 2022 Educational Concepts, L.L.C. dba Brief Media ™ All Rights Reserved. Terms & Conditions | DMCA Copyright | Privacy Policy | Acceptable Use Policy