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Therapeutics Research Note: GC-7101

Integrative Medicine

|February 2017

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Flos Lonicerae Japonicae is an herb used in Chinese medicine for heat-clearing, detoxification, anti-inflammation, throat pain, and GI motility disorder. GC-7101, the standardized extract of the herb, has a prokinetic effect on GI motility. This prokinetic effect has been demonstrated in laboratory studies by enhanced contractile response of feline esophageal smooth muscle, enhanced contractility of the feline lower esophageal sphincter, and accelerated gastric emptying and GI transit in rats. 

The authors suggested that there is potential for use of GC-7101 in developing new prokinetic drugs; however, further studies are needed.


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