Hepatobiliary Disease

Hepatobiliary disease encompasses a wide range of disorders that affect numerous systems. Elevated liver enzymes may be the first indication of a problem, but deciding how to proceed can sometimes seem overwhelming. This resource is meant to guide clinicians in their decision-making process when faced with suspected or confirmed hepatobiliary disease in their patients.

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ALP is a sensitive but relatively nonspecific marker of hepatobiliary disease. Review practical strategies for determining the clinical significance of elevated total ALP in dogs.

Stained histopathology slide of the liver.

Serum ALT and AST are the most sensitive screening markers for hepatocellular injury but do not assess liver function. Learn how to interpret transaminase elevations with confidence.

A grayscale ultrasound image shows a cross-sectional view of a canine abdomen, highlighting a fluid-filled structure that may represent a cyst or an organ. The surrounding tissue appears echogenic, indicating potential inflammation or pathology.

Hepatobiliary imaging can be essential for differential diagnoses in cats and dogs. This gallery explores the uses of both radiography and ultrasonography in the biliary system.

Ultrasound image of a mass within the right liver lobe in a dog with hepatocellular carcinoma.

Hepatobiliary imaging can be essential for differential diagnoses in cats and dogs. This gallery explores the uses of both radiography and ultrasonography to assess the liver.

Gallbladder mucoceles showing kiwi-like appearance on ultrasound.

Biliary diseases are becoming more commonly diagnosed in dogs and may warrant urgent surgical care. Explore 5 of the most common canine biliary diseases and how to diagnose, treat, and manage each.

A close-up of a brown dog's nose resting on a surface, with the dog's eyes partially visible in the background. The image highlights the texture of the dog's snout and emphasizes its relaxed state, suggesting a calm environment.

An 8-year-old Irish setter was presented for lethargy, anorexia, and intermittent head bobbing. Pancreatitis was diagnosed, and he was hospitalized; neurologic status continued to decline. What was the appropriate course of action for this case?

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SPONSORED BY NUTRAMAX

In this webinar, Dr. David C. Twedt will review how to identify and manage these conditions, as well as how to determine their etiology.

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SPONSORED BY BLUE BUFFALO

This webinar with Dr. John P. Loftus will explore the critical role of diet in managing liver conditions in dogs and cats and offer a comprehensive guide to the best nutritional strategies.

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Icterus typically indicates significant hyperbilirubinemia and serious disease. This retrospective study reviewed the cases of 115 dogs with hyperbilirubinemia to identify the patterns that determine prognosis.

old dog with graying whiskers

FNA of the liver has the advantage of cost and safety over biopsy, but falls short when it comes to detecting hepatitis. A retrospective study looked for ways to optimize hepatic cytology to detect inflammatory conditions.

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Hepatic lipidosis is a common liver disease in cats that is associated with high morbidity and mortality. Discover which clinical markers are associated with a poor prognosis.

A close-up of an orange tabby cat with bright green eyes, gazing thoughtfully to the side. The background is softly blurred, emphasizing the cat's attentive expression and the texture of its fur.

Postattenuation neurologic syndrome (PANS) after portosystemic shunt attenuation appears to affect cats more often than dogs. Discover what this study uncovered when evaluating the risk factors for these patients.

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Effective therapy starts with careful selection. Discover the top 5 antibiotics to consider when treating gastrointestinal and hepatobiliary disorders.

Feline patient on exam table with IV catheter.

Early, aggressive intervention can make all the difference for cats with hepatic lipidosis. Follow this case for practical diagnostic and treatment guidance, including a convenient chart to ensure safe food reintroduction and to minimize the risk for refeeding syndrome.

A veterinarian's hand is gently pulling back the lip of a dog, revealing yellowed teeth and darkened gums, indicating potential dental disease. The dog's face is partially visible, showcasing its wrinkled skin and short muzzle.

Hyperbilirubinemia doesn’t always signify hepatic disease; prehepatic and posthepatic causes should also be considered. Make sure you don't miss a differential by bookmarking this comprehensive yet straightforward list.

A gray tabby cat lies on a stainless steel examination table, with a breathing apparatus connected to its face. An intravenous line is attached to the cat, indicating it is undergoing a medical procedure or anesthesia.

Carefully selecting a protocol and various perianesthetic interventions are important to minimize adverse effects in patients with liver disease.