Two subadult, feral iguanas were captured in Florida. They were inappetent and had signs of constipation, pneumonia, and hindlimb weakness. One iguana died, and 1 was euthanized. At necropsy there were multifocal abscesses of the coccygeal and thoracic vertebrae. Numerous other lesions included coelomitis, enteritis, megacolon, and mixed bacterial septicemia. Along with other organisms, numerous mycoplasmas were cultured. Mycoplasma iguanae proposed species nova was isolated from vertebral abscesses and evaluated for sensitivity to a variety of antibiotics. Clindamycin, doxycycline, oxytetracycline, and tylosin were bacteriostatic from 0.1 to 0.5 µg/ml, and enrofloxacin was bactericidal at 20 ng/ml. Although antibiotic efficacy in iguanas is poorly documented, this study suggests that several drugs might be effective in treating M iguanae infections. The most common illness seen in captive iguanas is bone disease, but nutritional deficiencies are usually the cause of the bone disease. It is possible that an infectious etiology may mimic or exacerbate these conditions. In vitro antibiotic susceptibility of Mycoplasma iguanae proposed sp. nov. isolated from vertebral lesions of green iguanas (Iguana iguana).

Westfall ME, Demcovitz DL, Plourdé DR, et al. J ZOO WILDLIFE MED 37:206-208, 2006.