The popularity and use of zonisamide in veterinary patients has rapidly increased in recent years.


Zonisamide is used as an anticonvulsant in dogs and cats.

  • Based on the author’s clinical experience, zonisamide may be effective when used as monotherapy or in conjunction with other anticonvulsants (eg, phenobarbital, potassium bromide, levetiracetam).
  • In some cases, zonisamide may reduce seizure frequency by up to 70% to 80%.1,2
  • Zonisamide is available in generic form, which makes it more affordable than when first introduced.

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