Syncope

Lisa Murphy, MVB, DVM, DACVECC, Friendship Hospital for Animals, Washington, DC

Reid Nakamura, DVM, DACVIM, DACVECC , IDEXX Laboratories* 

ArticleApril 20241 min read
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Following are differential diagnoses for patients presented with syncope.

Cardiac

  • Congestive heart failure

  • Cardiac tamponade secondary to pericardial effusion

  • Arrhythmias

    • Inherited ventricular arrhythmias (eg, boxer, Doberman pinscher, German shepherd dog)

    • Supraventricular or ventricular arrhythmias secondary to underlying cardiac disease

    • Sick sinus syndrome (eg, miniature schnauzer, dachshund, West Highland white terrier, cocker spaniel)

    • Bradyarrhythmias

      • High-grade atrioventricular block (usually geriatric large-breed dogs)

      • Complete or third-degree atrioventricular block

      • Atrial standstill (hyperkalemia should be ruled out)

  • Outflow obstruction (eg, subaortic stenosis, pulmonic stenosis, heartworm infection)

  • Congenital heart disease resulting in right-to-left shunting from concurrent pulmonary hypertension or complex heart disease (eg, reverse patent ductus arteriosus, reverse atrial septal defect, reverse ventricular septal defect, Tetralogy of Fallot)

  • Hypertrophic cardiomyopathy

  • Vasovagal syncope

  • Left atrial tear due to degenerative mitral valve disease

  • Dilated cardiomyopathy

Respiratory

  • Hypoxia

  • Pulmonary hypertension

  • Pulmonary thromboembolism

  • Pneumonia

  • Neoplasia

  • Upper airway obstruction (eg, tracheal or laryngeal collapse, laryngeal paralysis, geriatric onset laryngeal paralysis polyneuropathy, foreign body)

Hypertensive

  • Adrenal disease (eg, pheochromocytoma)

  • Renal disease

Hypotensive

  • Hypovolemia

  • Septic shock

  • Cardiogenic (rare)

Hematologic

  • Anemia

  • Hyperglobulinemia (eg, multiple myeloma, lymphoma)

  • Polycythemia

*At the time of writing, Dr. Nakamura was affiliated with Coast-to-Coast Cardiology.