Content continues after advertisement

Research Note: Tick Resistance

Clinician's Brief (Capsule)


|October 2015

Sign in to Print/View PDF

The brown dog tick, Rhipicephalus sanguineus sensu lato, which may actually include more than 1 species, is a vector of the hemoparasites Babesia vogeli, Ehrlichia canis, and Hepatozoon canis and can also cause direct damage (eg, anemia, eczema, flaccid paralysis) to hosts. Tick control is primarily achieved with acaricides that act as broad-spectrum neurotoxins; however, overuse of these agents has led to acaricide resistance. Some animals are “tick-resistant” and produce signaling chemicals (semiochemicals) that mediate the behavioral biology of the tick and naturally control parasitism. There are conflicting reports about whether domestic dogs are capable of such tick resistance. Recent evidence suggests that tick resistance depends on breed of dog; ticks feeding on beagles were under-developed compared to those feeding on English cocker spaniels. The purpose of this study was to identify semiochemicals from beagles that may mediate repellency against R sanguineus. The investigators performed chemical analysis on beagle- and cocker spaniel-odor extracts using coupled high-resolution gas chromatography-mass spectrometry and Petri dish and olfactometer behavioral assays to assess the response of ticks to identified compounds. The beagle-odor extracts contained almost 3 times as many chemical compounds as cocker spaniel samples, with 2-hexanone, benzaldehyde, and undecane found to be repellant for R sanguineus. Findings from this study may enable development of new products for control of this particular tick species.


For global readers, a calculator to convert laboratory values, dosages, and other measurements to SI units can be found here.

All Clinician's Brief content is reviewed for accuracy at the time of publication. Previously published content may not reflect recent developments in research and practice.

Material from Clinician's Brief may not be reproduced, distributed, or used in whole or in part without prior permission of Educational Concepts, LLC. For questions or inquiries please contact us.


Clinician's Brief:
The Podcast
Listen as host Alyssa Watson, DVM, talks with the authors of your favorite Clinician’s Brief articles. Dig deeper and explore the conversations behind the content here.
Clinician's Brief provides relevant diagnostic and treatment information for small animal practitioners. It has been ranked the #1 most essential publication by small animal veterinarians for 9 years.*

*2007-2017 PERQ and Essential Media Studies

© 2023 Educational Concepts, L.L.C. dba Brief Media ™ All Rights Reserved. Terms & Conditions | DMCA Copyright | Privacy Policy | Acceptable Use Policy