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Quiz: Systemic Fungal Diseases

Johanna Heseltine, DVM, MS, DACVIM (Small Animal), Texas A&M University

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Quiz: Systemic Fungal Diseases

This quiz reviews the presentation, diagnosis, and treatment of systemic fungal diseases in dogs and cats. Blastomyces dermatitdis, Histoplasma capsulatum, Cryptococcus neoformans, and Coccidioides immitis are covered.

10  Questions
Multiple Choice Questions
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Quiz: Systemic Fungal Diseases

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1/10  Questions
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A 3-year-old castrated German shorthaired pointer from Tennessee was presented with a 3-month history of progressive lethargy and dry cough. Physical examination revealed generalized enlargement of the peripheral lymph nodes. Thoracic radiography showed a generalized nodular pattern. Cytology results of lymph node aspirate confirmed the presence of Blastomyces dermatitidis.

Considering efficacy, ease of administration, and potential for side effects, which of the following is the best treatment choice?

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Quiz: Systemic Fungal Diseases
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Of the following possible routes of transmission, which one could not transmit the fungal organism Blastomyces dermatitidis to veterinary personnel?

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Quiz: Systemic Fungal Diseases
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Which of the following samples is least likely to yield a cytology diagnosis of feline Histoplasma capsulatum infection?

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Quiz: Systemic Fungal Diseases
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A 5-year-old spayed domestic shorthaired cat from Oklahoma was presented with a 4-week history of lethargy and inappetence. She lives strictly indoors with one other cat. On physical examination, the patient was febrile (rectal temperature, 103.5oF [39.7oC]; reference, 101.5oF ± 1 [38.6oC ± 0.5]) and lethargic, and splenomegaly was evident on palpation. Abdominal radiography confirmed splenomegaly. Thoracic radiography revealed a generalized miliary interstitial pattern in the lungs. Cytology of fine-needle aspirate obtained from the spleen identified Histoplasma capsulatum

What is the most likely source of infection in this cat?

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Quiz: Systemic Fungal Diseases
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Regarding treatment of the disseminated fungal infection found in the cat discussed in Question 4, which of the following statements is most accurate?

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Quiz: Systemic Fungal Diseases
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Which of the following is not an expected clinical sign in cats with Cryptococcus neoformans infection?

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Quiz: Systemic Fungal Diseases
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Measurement of serum polysaccharide capsular antigen by latex agglutination testing can be useful in the diagnosis of feline cryptococcosis.

Which of the following statements regarding this test is least accurate?

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Quiz: Systemic Fungal Diseases
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A 5-year-old, neutered male, indoor-outdoor Siamese cat was presented with an 8-month history of lethargy, nasal congestion, and mucopurulent nasal discharge from the right nostril. Treatment with amoxicillin-clavulanate had yielded no effect. The cat is current on vaccinations and tested negative for FeLV and FIV. On physical examination, mucopurulent discharge from the right nostril was evident, with no airflow through that naris. A CT scan showed a contrast-enhancing soft tissue mass lesion with bony lysis and extension through the cribriform plate. Cytology of the nasal mass confirmed the presence of Cryptococcus spp.

Which of the following drug combinations is the treatment of choice for this cat?

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Quiz: Systemic Fungal Diseases
9/10  Questions
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A 6-year-old intact male Labrador retriever from Arizona was presented with a 3-month history of a dry, harsh cough. The dog is housed predominantly outdoors with another field trial dog that has shown no signs of illness. On physical examination, the patient’s rectal temperature was 102.8oF (39.3oC), and nonproductive cough is observed. A draining tract between the second and third digit of the right hindlimb was evident, along with enlargement of the popliteal lymph node. Cytology of a fine-needle aspirate of the lymph node confirmed Coccidioides immitis. Thoracic radiography showed a generalized interstitial pattern with hilar lymphadenopathy.

Which of the following is not a risk factor for this systemic fungal infection in dogs?

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Quiz: Systemic Fungal Diseases
10/10  Questions
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Which of the following combined coccidioidomycosis titers with paired interpretation is least accurate?

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Quiz: Systemic Fungal Diseases
10/10  Questions
Multiple Choice Questions
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Quiz: Systemic Fungal Diseases

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