This study sought to update seroprevalence information and to identify risk factors associated with seropositivity for FeLV antigen and anti-FIV antibody in cats in the United States and Canada.
Over a 7-month period in 2010, point-of-care ELISA for FeLV antigen and anti-FIV antibody tests were conducted on 62 301 cats from 1396 veterinary clinics and 127 animal shelters. Seroprevalence was 3.1% for FeLV antigen and 3.6% for anti-FIV antibody, slightly higher than tests performed in 2004.4 Adult age, outdoor access, clinical disease, and being a sexually intact male were identified as risk factors for seropositivity for each virus. Retroviral seropositivity was present in cats with oral disease (4.7% for FeLV and 9.7% for FIV), respiratory disease (8% for FeLV and 6.4% for FIV), and abscesses or bite wounds (5.5% for FeLV and 12.5% for FIV).
Results indicated that seroprevalence of these retroviruses, at a minimum, did not decline in North America between 2004 and 2010. Results also indicated a need for veterinarians and shelter managers to improve compliance with existing guidelines for management of FeLV and FIV. Guidelines include testing of all owned cats, retesting of cats that develop disease or that may have been exposed to infected cats, vaccinating against FeLV for all kittens and for adult cats at risk for exposure, segregating infected cats, and spaying/neutering of unowned free-roaming cats.3