- Feline infectious peritonitis (FIP), characterized as an immune-mediated pyogranulomatous vasculitis, is a fatal infection caused by virulent feline coronavirus (FCoV).1-3
Related Article: FIP Update: Hope for the Future
- FIP commonly affects abdominal organs.
- Thoracic organs, the eyes, and the CNS can be also affected.1,2
- A polygenic mode of inheritance has been suggested, and heritability is reportedly >50% in some pedigree catteries.4-6
Incidence & Prevalence
- FCoV infection is highly prevalent, especially in crowded environments (eg, catteries, shelters).7
- Approximately 25% of cats in single-cat households and 75%–90% in multicat households have antibodies to (and are serologically positive for) FCoV.4
- Reportedly, 7.8%–12% of FCoV-infected cats may develop FIP.2,4
- It has been suggested that FIP mortality may be ~5% in densely populated environments but much lower in households with 1–2 cats.4,7
- FIP is found worldwide, as FCoV is ubiquitous among domestic cats.
- Wild felid populations may also become infected.1