Deep, Progressing Corneal Ulcer with Secondary Anterior Uveitis

Prince, a 6-year-old neutered male shih tzu, was presented with a 3-week history of blepharospasm of the right eye. Abnormal ocular examination findings were limited to the right eye and included mild blepharospasm, moderate epiphora and mucopurulent discharge, conjunctival injection, diffuse corneal edema, fluorescein-stainpositive paracentral corneal ulceration (6 4 mm; estimated depth, 40%), corneal neovascularization, yellow-green corneal infiltrate in the ulcer bed, miotic pupil, intraocular pressure of 5 mm Hg (left eye, 15 mm Hg), and mild aqueous flare. Corneal cytology revealed neutrophils and rod-shaped bacteria. Results of corneal culture and susceptibility testing are pending. Physical examination, including of the left eye, was otherwise unremarkable.

MMP = matrix metalloproteinase, NSAID = nonsteroidal anti-inflammatory drug