In this episode, host Alyssa Watson, DVM, is joined by Lauren R. Forsythe, PharmD, DICVP, FSVHP, to talk about her recent Clinician’s Brief article, “Top 3 Compounded Drugs That Can Be Administered Transdermally in Cats.” Dr. Forsythe shares the pharmacist side of this topic, explaining the advantages and limitations of transdermal delivery. She also discusses some drugs that show good evidence of transdermal dosing in cats, as well as ones that are questionable or inappropriate.
Key Takeaways
The goal of transdermal medication is to make it more doable for some clients and patients, particularly cats.
Transdermal absorption typically takes much longer and leads to lower blood levels than oral absorption.
Using penetration enhancers and drugs with small molecular size can improve penetration through the stratum corneum.
There is evidence for transdermal delivery of methimazole and phenobarbital in cats, but it is not appropriate for antibiotics.
Alternating ears is recommended, as well as cleaning off the prior dose before applying the next one.
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The Team:
Alyssa Watson, DVM - Host
Alexis Ussery - Producer & Multimedia Specialist