Content continues after advertisement

Differential Diagnosis: Hypercholesterolemia

Julie Allen, BVMS, MS, MRCVS, DACVIM (SAIM), DACVP, Cornell University

Internal Medicine

|February 2019|Peer Reviewed

Sign in to Print/View PDF

Differential Diagnosis: Hypercholesterolemia

Following are differential diagnoses, listed in order of likelihood, for patients presented with hypercholesterolemia.

  • Hemolysis (false increase with marked hemolysis)
  • Postprandial (mild, typically does not exceed the reference interval)
  • Obesity
  • Certain high-fat diets (dogs only; meat-based diets only)
  • Hypothyroidism
  • Diabetes mellitus
  • Hyperadrenocorticism
  • Cholestasis
  • Pancreatitis (hypertriglyceridemia more common)
  • Familial hyperlipidemia of miniature schnauzers (primarily hypertriglyceridemia)
  • Nephrotic syndrome (in combination with hypoalbuminemia, proteinuria, and edema)
  • Familial hypercholesterolemia (Briards, rottweilers, Doberman pinschers, rough collies, Shetland sheepdogs)
  • Inherited hyperchylomicronemia (in cats; primarily hypertriglyceridemia)


For global readers, a calculator to convert laboratory values, dosages, and other measurements to SI units can be found here.

Material from Clinician's Brief may not be reproduced, distributed, or used in whole or in part without prior permission of Educational Concepts, LLC. For questions or inquiries please contact us.


Clinician's Brief:
The Podcast

Listen as host Beckie Mossor, RVT, talks with the authors of your favorite Clinician’s Brief articles. Dig deeper and explore the conversations behind the content here.
Clinician's Brief provides relevant diagnostic and treatment information for small animal practitioners. It has been ranked the #1 most essential publication by small animal veterinarians for 9 years.*

*2007-2017 PERQ and Essential Media Studies

© Educational Concepts, L.L.C. dba Brief Media ™ All Rights Reserved. Privacy Policy (Updated 05/08/2018) Terms of Use (Updated 05/08/2018)