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What is Atinvicitinib?
Atinvicitinib is a new treatment option for management of allergic dermatitis, including atopic dermatitis, in dogs.1-3
Pharmacology of Atinvicitinib
Atinvicitinib is a Janus kinase (JAK) inhibitor with a high selectivity for JAK1. By inhibiting JAK1, atinvicitinib inhibits the function of various proinflammatory, pruritogenic, and allergy-related cytokines.
Contraindications of Atinvicitinib
Atinvicitinib is contraindicated in dogs hypersensitive to it. The drug has not been studied in dogs that are pregnant, lactating, or intended for breeding or in other species.
Adverse Effects of Atinvicitinib
Atinvicitinib appears to be well tolerated. Adverse effects (eg, nausea, vomiting, diarrhea, anorexia, lethargy) were reported in <10% of dogs.1
Additional Information
Atinvicitinib does not impair the immune response to vaccination.1
A comprehensive look at how to manage allergic dermatitis in dogs is offered by the experts at Standards of Care (paid subscription only).