A 6-year-old neutered Cavalier King Charles spaniel was presented with a 2-week history of difficulty climbing stairs and jumping into the car.  


The Cavalier King Charles spaniel (CKCS) had a previous diagnosis of a grade III/VI left systolic heart murmur.

Physical Examination

The heart murmur as previously described was detected. Instability in the left stifle was also noted. The remainder of the examination was unremarkable.

Laboratory Evaluation

CBC was unremarkable with the exception of an automated platelet count of 2350/µL (reference interval, 181–525 ¥ 103/µL; Cell-Dyn 3500 hematology analyzer using impedance technology for platelet count). A blood smear was evaluated.

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