Hyperadrenocorticism in dogs, also called canine Cushing’s syndrome (CCS), is a clinical syndrome with biochemical abnormalities resulting from excess cortisol production by the adrenal glands.1,2

The prevalence of CCS in the general population of dogs in the United States is approximately 0.1%.3

The initial index of suspicion results from history, clinical signs, and a minimum database; it should not be diagnosed without endocrine testing.1,3-6

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