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The Tolerability & Palatability of UC-II® for Feline Patients



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The Tolerability & Palatability of UC-II® for Feline Patients

Sponsored by Vetoquinol

More than 90% of feline veterinary patients have radiographic joint changes.1 Careful monitoring indicates that despite a lack of obvious lameness, it is possible to detect signs of discomfort and response to therapy in feline patients with joint issues.2,3 

90% of cats have radiographic signs of joint changes.

90% of cats have radiographic signs of joint changes.

During the study, each cat was offered a joint supplement containing UC-II® (Flexadin Advanced®) for 40 days, and consumption was monitored over 15 minutes.

Seventy percent of the 33 cats took the supplement voluntarily, generally within the first 5 minutes. Patients tolerated the supplement well; no remarkable changes were noted on physical examination and no changes in bodyweight were observed.4

UC-II® Proposed Mechanism

70% of cats consumed within 5 minutes.

  • Inflammation reduced through oral tolerance.
  • Similar mechanism to that used to prevent immune response to food proteins.

UC-II® reduces inflammation by inducing immune tolerance to help break the cycle of discomfort and inflammation. It has been studied in humans, horses, and dogs as a potential therapy for addressing joint issues.5-9

The present study shows Flexadin® Advanced is a safe, palatable joint supplement option for cats.


For global readers, a calculator to convert laboratory values, dosages, and other measurements to SI units can be found here.

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