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Image Gallery: Immune-Mediated Skin Diseases

Alison Diesel, DVM, DACVD, Texas A&M University


|August 2020|Peer Reviewed|Web-Exclusive

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Immune-mediated skin diseases (ie, pemphigus foliaceus, discoid lupus erythematosus, erythema multiforme, immune-mediated vasculitis, plasma cell pododermatitis) are uncommon but should be considered in patients that have symmetrically distributed lesions, affected nonhaired skin (eg, foot pad, nasal planum, mucous membrane), and a lack of response to nonimmune-mediated disease therapy. Biopsy is considered the gold standard for diagnosis of these conditions. Patients presented with dermatologic concerns should first be evaluated for common pruritic skin diseases caused by ectoparasites (eg, sarcoptic mange, demodicosis), infections (eg, bacterial pyoderma, Malassezia spp dermatitis, dermatophytosis), and/or allergies (eg, flea allergy dermatitis, food allergy, atopic dermatitis).

Following are examples of immune-mediated skin diseases that might be encountered in small animal practice.


For global readers, a calculator to convert laboratory values, dosages, and other measurements to SI units can be found here.

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