Newer-generation topical (spot-on) ectoparasiticides for companion animals have significantly improved efficacy against fleas and ticks compared with the shampoos and dips of the recent past.1
Tepoxalin was evaluated in vivo with angiotensin-converting enzyme inhibitors (ACE-Is) to assess renal function in dogs.1 Renal function was not altered.
Lyme disease is the most commonly reported vector-borne disease in humans and has been increasing in frequency and distribution since it was first recognized in 1975.
Developed specifically for veterinary use, firocoxib has a higher selectivity for COX-2 and a substantially greater sparing of COX-1 than previously available agents.
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