Anticoagulant Rodenticide Ingestion

ArticleLast Updated June 20151 min readPeer Reviewed

The EPA has banned public use of brodifacoum, bromadiolone, difenacoum, and difethialone. These products were manufactured for home use until December 31, 2014, and shipped until March 2015. The new products contain diphacinone, and 4 weeks of vitamin K1 therapy is currently recommended to treat this anticoagulant rodenticide (ACR). These changes may decrease ACR toxicities and increase cases of other rodenticide toxicities, particularly bromethalin, which can cause neurotoxicity. 

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LORI S. WADDELL, DVM, DACVECC, is adjunct associate professor in critical care at University of Pennsylvania’s intensive care unit. Her areas of interest include colloid osmotic pressure, acid-base disturbances, and coagulation in critically ill patients. She has published numerous original papers and book chapters on various critical care topics. A graduate of Cornell University, she was emergency clinician in private practice until beginning a residency in emergency medicine and critical care at University of Pennsylvania.